Barcelona are looking a little short in central defence with Clement Lenglet suspended and Samuel Umtiti injured.
Left-back is also a problem with Jordi Alba and Junior Firpo on the sidelines, meaning Nelson Semedo and Sergi Roberto could be forced to use their versatility once again.
But Lionel Messi could start just his second league match of the campaign following his most recent injury setback.
Meanwhile, Sevilla have a full-strength squad and will likely start ex-Barcelona forward Munir El Haddadi.
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